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Exercise as a Therapy in Adults With Multiple Sclerosis

Key Message

Exercise improves walking speed and endurance in patients with multiple sclerosis. 

Source

Pearson, Melissa, Dieberg, Gudrun, and Smart, Niel. (2015). Exercise as a Therapy for Improvement of Walking Ability in Adults With Multiple Sclerosis: A Meta-Analysis. Archives of Physical Medicine and Rehabilitation. 96(7): 1339–1348.e7. doi:10.1016/j.apmr.2015.02.011

Purpose

To quantify improvements in walking performance commonly observed in patients with multiple sclerosis (pwMS). 

Evidence

Data from 13 studies were included. In pwMS who exercised, significant improvements were found in walking speed, measured by the 10mWT (mean difference [MD] reduction in walking time of −1.76s; 95% confidence interval [CI], −2.47 to −1.06; P<.001), but no change in the T25FW (MD=−.59s; 95% CI, −2.55 to 1.36; P=.55). In pwMS who exercised, significant improvements were found in walking endurance as measured by the 6MWT and 2MWT, with an increased walking distance of MD=36.46m (95% CI, 15.14–57.79; P<.001) and MD=12.51m (95% CI, 4.79–20.23; P=.001), respectively. No improvement was found for TUG (MD=−1.05s; 95% CI, −2.19 to .09; P=.07).

Benefit Statements / Outcomes

Leadership Provided By:

  • Leisure Information Network (LIN)
  • Alberta Recreation and Parks Association

On Behalf Of:

  • Canadian Parks and Recreation Association (CPRAA)

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