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Higher Fitness Reduces Risk of Death after first Heart Attack

Key Message

Higher baseline exercise capacity was independently associated with a lower risk of early death after a first myocardial infarction. 


Shaya, Gabriel E. et al. (2016). High Exercise Capacity Attenuates the Risk of Early Mortality After a First Myocardial Infarction. Mayo Clinic Proceedings. 91(2): 129–139. DOI:


To examine the effect of objectively measured exercise capacity (EC) on early mortality (EM) after a first myocardial infarction (MI).


The 28-day EM rate was 10.6% overall, and 13.9%, 10.7%, 6.9%, and 6.0% in the less than 6, 6 to 9, 10 to 11, and 12 or more METs categories, respectively (P<.001). Patients who died were more likely to be older, be less fit, be nonobese, have treated hypertension, and have a longer duration from baseline to incident MI (P<.05). Adjusted regression analyses revealed a decreased risk of EM with increasing EC categories. A 1-MET higher EC was associated with an 8% to 10% lower risk of mortality across all time points (28 days: odds ratio [OR], 0.92; 95% CI, 0.87-0.98; P=.006; 90 days: OR, 0.90; 95% CI, 0.86-0.95; P<.001; 365 days: OR, 0.91; 95% CI, 0.87-0.94; P<.001).

Benefit Statements / Outcomes

Leadership Provided By:

  • Leisure Information Network (LIN)
  • Alberta Recreation and Parks Association

On Behalf Of:

  • Canadian Parks and Recreation Association (CPRAA)

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