Higher Fitness Reduces Risk of Death after first Heart Attack
Higher baseline exercise capacity was independently associated with a lower risk of early death after a first myocardial infarction.
Shaya, Gabriel E. et al. (2016). High Exercise Capacity Attenuates the Risk of Early Mortality After a First Myocardial Infarction. Mayo Clinic Proceedings. 91(2): 129–139. DOI: http://dx.doi.org/10.1016/j.mayocp.2015.11.012
To examine the effect of objectively measured exercise capacity (EC) on early mortality (EM) after a first myocardial infarction (MI).
The 28-day EM rate was 10.6% overall, and 13.9%, 10.7%, 6.9%, and 6.0% in the less than 6, 6 to 9, 10 to 11, and 12 or more METs categories, respectively (P<.001). Patients who died were more likely to be older, be less fit, be nonobese, have treated hypertension, and have a longer duration from baseline to incident MI (P<.05). Adjusted regression analyses revealed a decreased risk of EM with increasing EC categories. A 1-MET higher EC was associated with an 8% to 10% lower risk of mortality across all time points (28 days: odds ratio [OR], 0.92; 95% CI, 0.87-0.98; P=.006; 90 days: OR, 0.90; 95% CI, 0.86-0.95; P<.001; 365 days: OR, 0.91; 95% CI, 0.87-0.94; P<.001).