Sports-based program for inactive men improved diabetes risk factors
Sport and group-based activities lead to improved clinical risk factors associated with Type 2 diabetes mellitus development in clinically obese Indigenous Australian men.
Mendham, Amy E. et al. (2014). A 12-week sports-based exercise program for inactive Indigenous Australian men improved clinical risk factors associated with type 2 diabetes mellitus. Journal of Science and Medicine in Sport. Available online July 2014. DOI: 10.1016/j.jsams.2014.06.013
This study assessed the impact of a 12-week sports-based exercise intervention on glucose regulation, anthropometry and inflammatory markers associated with the prevalence of type 2 diabetes mellitus (T2DM) in Indigenous Australian men.
Twenty-six inactive Indigenous Australian men were randomized into an exercise (n = 16) or control (n = 10) conditions. Training included ∼2-3 days/week for 12 weeks of sports and gym exercises in a group environment, whilst control participants maintained normal activity and dietary patterns. Pre- and post-intervention testing included: anthropometry, peak aerobic capacity, fasting blood chemistry of inflammatory cytokines, adiponectin, leptin, cholesterol, glucose, insulin and C-peptide. An oral glucose tolerance test measured glucose, insulin and C-peptide 30, 60, 90 and 120 min post 75 g glucose ingestion.
The exercise condition decreased insulin area under the curve (25 ± 22%), increased estimated insulin sensitivity (35 ± 62%) and decreased insulin resistance (9 ± 35%; p < 0.05), compared with control (p > 0.05). The exercise condition decreased in body mass index, waist circumference and waist to hip ratio (p < 0.05), compared to control (p > 0.05). Leptin decreased in the exercise group, with no changes for adiponectin (p > 0.05) or inflammatory markers (p > 0.05) in either condition. Aerobic fitness variables showed significant increases in peak oxygen consumption for the exercise condition compared to no change in control (p > 0.05).Conclusion